In 1891 London, Sherlock Holmes (Robert Downey, Jr.) and Dr. John Watson (Jude Law) race to prevent the ritual murder of a girl by Lord Blackwood (Mark Strong), who has killed five other people similarly. They are able to stop the murder just in time before Inspector Lestrade (Eddie Marsan) and the police arrive to make the arrest. Three months later, Blackwood is sentenced to death and requests to see Holmes, who visits him in prison. He warns Holmes of three more impending deaths that will cause great changes to the world. Blackwood is hanged and pronounced dead by Dr. Watson.
Holmes receives a surprise visit at 221B Baker Street from Irene Adler (Rachel McAdams), a professional thief and his former adversary, who asks him to find a missing man named Reordan. After her departure, Holmes discreetly follows her as she meets with a man, her secret employer, hidden in the shadows of a carriage. The concealed man states that Reordan is the key to Blackwood's plans.
Three days later, Blackwood's tomb is destroyed from the inside out. Reordan is found dead inside Blackwood's coffin. A groundskeeper claims to have seen Blackwood walking from the tomb. Following a series of clues from the body, Holmes and Watson find Reordan's home and discover experiments attempting to merge science with magic. Later, Holmes is taken to the Temple of the Four Orders, an occult-dabbling secret society. The leaders, Sir Thomas (James Fox) and Home Secretary Lord Coward (Hans Matheson), ask Holmes to stop Blackwood, a former member of the Order. Sir Thomas and another senior member of the group are later killed through apparently supernatural means by Blackwood, allowing him to assume control. He plans to push for Britain to retake the United States, weakened by civil war. Lord Coward, who has been in league with Blackwood all along, issues a warrant for Holmes' arrest.
When Holmes learns he is wanted by the police he goes into hiding and studies Blackwood's rituals, concluding the next target is British Parliament. Holmes tricks Lord Coward into revealing that the plan is to wipe out the House of Lords and then rejoins Adler and Watson. The three sneak into the sewers beneath Parliament and discover a machine, based on Reordan's experiments, designed to release a cyanide derivative into the Parliament chambers. They fight off Blackwood's men, and remove the cyanide containers from the machine. Adler grabs the cylinders and races away, pursued by Holmes. Blackwood and Coward realise their plan has failed. Coward is captured but Blackwood manages to escape.
Holmes confronts Adler on top of the incomplete Tower Bridge but is interrupted by Blackwood. Holmes tricks him into becoming entangled in the ropes and chains, hanging over the Thames while Holmes recounts the technical trickery behind all of Blackwood's supposed magic. A loose beam falls off the rafter supports, causing Blackwood to fall and unintentionally hang himself.
Adler explains that her employer is Professor Moriarty, warning that Moriarty is every bit as intelligent as Holmes but far more devious. Later, the police report to Holmes and Watson that a dead officer was found near Blackwood's device. Professor Moriarty used the confrontations with Adler and Blackwood as a diversion while he took a key component from the machine. This prompts Holmes to accept the new case whilst refusing an offer to name his own fee.
Holmes receives a surprise visit at 221B Baker Street from Irene Adler (Rachel McAdams), a professional thief and his former adversary, who asks him to find a missing man named Reordan. After her departure, Holmes discreetly follows her as she meets with a man, her secret employer, hidden in the shadows of a carriage. The concealed man states that Reordan is the key to Blackwood's plans.
Three days later, Blackwood's tomb is destroyed from the inside out. Reordan is found dead inside Blackwood's coffin. A groundskeeper claims to have seen Blackwood walking from the tomb. Following a series of clues from the body, Holmes and Watson find Reordan's home and discover experiments attempting to merge science with magic. Later, Holmes is taken to the Temple of the Four Orders, an occult-dabbling secret society. The leaders, Sir Thomas (James Fox) and Home Secretary Lord Coward (Hans Matheson), ask Holmes to stop Blackwood, a former member of the Order. Sir Thomas and another senior member of the group are later killed through apparently supernatural means by Blackwood, allowing him to assume control. He plans to push for Britain to retake the United States, weakened by civil war. Lord Coward, who has been in league with Blackwood all along, issues a warrant for Holmes' arrest.
When Holmes learns he is wanted by the police he goes into hiding and studies Blackwood's rituals, concluding the next target is British Parliament. Holmes tricks Lord Coward into revealing that the plan is to wipe out the House of Lords and then rejoins Adler and Watson. The three sneak into the sewers beneath Parliament and discover a machine, based on Reordan's experiments, designed to release a cyanide derivative into the Parliament chambers. They fight off Blackwood's men, and remove the cyanide containers from the machine. Adler grabs the cylinders and races away, pursued by Holmes. Blackwood and Coward realise their plan has failed. Coward is captured but Blackwood manages to escape.
Holmes confronts Adler on top of the incomplete Tower Bridge but is interrupted by Blackwood. Holmes tricks him into becoming entangled in the ropes and chains, hanging over the Thames while Holmes recounts the technical trickery behind all of Blackwood's supposed magic. A loose beam falls off the rafter supports, causing Blackwood to fall and unintentionally hang himself.
Adler explains that her employer is Professor Moriarty, warning that Moriarty is every bit as intelligent as Holmes but far more devious. Later, the police report to Holmes and Watson that a dead officer was found near Blackwood's device. Professor Moriarty used the confrontations with Adler and Blackwood as a diversion while he took a key component from the machine. This prompts Holmes to accept the new case whilst refusing an offer to name his own fee.
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